Fluocinolone acetonide ( NSC 92339 )

产品货号. M15588 CAS No. 67-73-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Fluocinolone acetonide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Fluocinolone Acetonide 是一种与胞质糖皮质激素受体结合的皮质类固醇。
产品描述

Fluocinolone Acetonide is a corticosteroid that binds to the cytosolic glucocorticoid receptor.
体外实验

Cell Proliferation Assay Cell Line:DCPs Concentration:0.1 μmol/L, 1 μmol/L, 10 μmol/L, 20 μmol/L, 40 μmol/L, 60 μmol/L, 100 μmol/L Incubation Time:24 h Result:Significantly promoted the growth rate of DPCs of a low concentration.Western Blot Analysis Cell Line:DCPs Concentration:1 μmol/L, 10 μmol/L Incubation Time:7 days Result:Showed higher expressions of DSPP and Wnt4 protein than negative control.
体内实验

Animal Model:PTX-induced peripheral neuropathy model Dosage:500 μg/kg Administration:Intraperitoneal injection (i.p.)Result:Prevented a marked reduction in intraepidermal nerve fibers density in the plantar surface of the hind paws.
同义词

NSC 92339
通路

Others
靶点

Other Targets
受体

Others
研究领域

Inflammation/Immunology
适应症

——

CAS Number

67-73-2
分子量

452.49
分子式

C24H30F2O6
纯度

>98% (HPLC)
溶解度

Ethanol: 12 mg/mL (26.51 mM); DMSO: 90 mg/mL (198.89 mM)
SMILES

O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@]4(C)[C@]5(C(CO)=O)OC(C)(C)O[C@]5([H])C[C@@]4([H])[C@]3([H])C[C@H](F)C2=C1
化学全称

(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

计算器

产品手册

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